Illudin M

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Illudin M 是一种细胞毒性真菌倍半萜，可以从 Omphalotus illudens 蘑菇培养基中分离得到的。Illudin M 能使 DNA 烷基化。Illudin M 具有抗肿瘤活性。

Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus illudens mushrooms. Illudin M can alkylate DNA. Illudin M has anti-tumor activities.

Illudin M (0.01-10 μM; 24-120 hours) shows cytotoxicity and induction of apoptosis in vitro.Apoptosis Analysis Cell Line:Panc-1 pancreatic carcinoma, HT-29 colon adenocarcinoma, non-malignant human foreskin fibroblasts (HFs) Concentration:0.01 μM, 1 μM, 10 μM Incubation Time:24 hours, 48 hours,72 hours, 96 hours, 120 hours Result:Showed a comparable induction of apoptosis in the tumour cells (86% in Panc-1; 48% in HT-29), but an even greater one in the HF (89%).

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Others

Other Targets

DNA Alkylator/Crosslinker | Apoptosis

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1146-04-9

248.32

C15H20O3

>98% (HPLC)

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CC1=C2[C@@H](O)C(C)(C)C=C2C(=O)[C@](C)(O)C11CC1

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(-20℃)

With Ice Pack

≥ 2 years